• Associations between epigenetic age acceleration and infertility 

      Lee, Yunsung; Bohlin, Jon; Page, Christian Magnus; Nustad, Haakon E.; Harris, Jennifer Ruth; Magnus, Per Minor; Magnus, Per; Jugessur, Astanand; Magnus, Maria Christine; Håberg, Siri Eldevik; Hanevik, Hans Ivar (Journal article; Peer reviewed, 2022)
      Study question: Is the use of ART, a proxy for infertility, associated with epigenetic age acceleration? Summary answer: The epigenetic age acceleration measured by Dunedin Pace of Aging methylation (DunedinPoAm) differed ...
    • Epigenome-wide association study of leukocyte telomere length 

      Lee, Yunsung; Sun, Dianjianyi; Ori, Anil P.S.; Lu, Ake T.; Seeboth, Anne; Harris, Sarah E.; Deary, Ian J.; Marioni, Riccardo E.; Sørensen, Mette; Mengel-From, Jonas; Hjelmborg, Jacob; Christensen, Kaare; Wilson, James G.; Levy, Daniel; Reiner, Alex P.; Chen, Wei; Li, Shengxu; Harris, Jennifer Ruth; Magnus, Per; Aviv, Abraham; Jugessur, Astanand; Horvath, Steve (Peer reviewed; Journal article, 2019)
      Telomere length is associated with age-related diseases and is highly heritable. It is unclear, however, to what extent epigenetic modifications are associated with leukocyte telomere length (LTL). In this study, we conducted ...
    • EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection 

      Lee, Yunsung; Riskedal, Espen; Kalleberg, Karl Trygve; Istre, Mette Stausland; Lind, Andreas; Lund-Johansen, Fridtjof; Reiakvam, Olaug Marie; Søraas, Arne Vasli; Harris, Jennifer Ruth; Dahl, John Arne; Lund Hadley, Cathrine; Jugessur, Astanand (Journal article; Peer reviewed, 2022)
      Although substantial progress has been made in managing COVID-19, it is still difficult to predict a patient’s prognosis. We explored the epigenetic signatures of COVID-19 in peripheral blood using data from an ongoing ...
    • Genetic association study of childhood aggression across raters, instruments, and age 

      Ip, Hill F.; van der Laan, Camiel M.; Krapohl, Eva M. L.; Brikell, Isabell; Sánchez-Mora, Cristina; Nolte, Ilja M.; Pourcain, Beate St; Bolhuis, Koen; Palviainen, Teemu; Zafarmand, Hadi; Colodro-Conde, Lucía; Gordon, Scott; Zayats, Tetyana; Aliev, Fazil; Jiang, Chang; Wang, Carol A.; Saunders, Gretchen; Karhunen, Ville; Hammerschlag, Anke R.; Adkins, Daniel E.; Border, Richard; Peterson, Roseann E.; Prinz, Joseph A.; Thiering, Elisabeth; Seppälä, Iikka; Vilor-Tejedor, Natàlia; Ahluwalia, Tarunveer S.; Day, Felix R.; Hottenga, Jouke-Jan; Allegrini, Andrea G.; Rimfeld, Kaili; Chen, Qi; Yi, Lu; Martin, Joanna; Soler Artigas, Marìa; Rovira, Paula; Bosch, Rosa; Español, Gemma; Ramos-Quiroga, Josep Antonio; Neumann, Alexander; Haavik, Jan; Harris, Jennifer Ruth; Helgeland, Øyvind; Johansson, Stefan; Knudsen, Gun Peggy Strømstad; Njølstad, Pål Rasmus; Havdahl, Alexandra; Magnus, Per Minor; Reichborn-Kjennerud, Ted; Boomsma, Dorret I. (Journal article; Peer reviewed, 2021)
      Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from ...
    • Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels 

      Lee, Yunsung; Choufani, Sanaa; Weksberg, Rosanna; Wilson, Samantha L.; Yuan, Victor; Burt, Amber; Marsit, Carmen; Lu, Ake T.; Ritz, Beate; Bohlin, Jon; Gjessing, Håkon K.; Harris, Jennifer Ruth; Magnus, Per; Binder, Alexandra M.; Robinson, Wendy P.; Jugessur, Astanand; Horvath, Steve (Peer reviewed; Journal article, 2019)
      The human pan-tissue epigenetic clock is widely used for estimating age across the entire lifespan, but it does not lend itself well to estimating gestational age (GA) based on placental DNAm methylation (DNAm) data. We ...
    • Retirement age and disability status as pathways to later-life cognitive impairment: Evidence from the Norwegian HUNT Study linked with Norwegian population registers 

      Zotcheva, Ekaterina; Strand, Bjørn Heine; Bowen, Catherine E; Bratsberg, Bernt Magne; Jugessur, Astanand; Engdahl, Bo Lars; Selbæk, Geir; Kohler, Hans-Peter; Harris, Jennifer Ruth; Weiss, Jordan; Grøtting, Maja Weemes; Tom, Sarah E.; Krokstad, Steinar; Stern, Yaakov; Håberg, Asta; Skirbekk, Vegard Fykse (Journal article; Peer reviewed, 2023)
      Background Research shows that retirement age is associated with later-life cognition but has not sufficiently distinguished between retirement pathways. We examined how retirement age was associated with later-life ...